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Structure-function relationships of estrogenic triphenylethylenes related to endoxifen and 4-hydroxytamoxifen,
P.Y. Maximov, C.B. Myers, R.F. Curpăn, J.S. Lewis-Wambi, V.C. Jordan,
J. Med. Chem., 2010, 53(8), 3273-3283.
Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs,
B. Ritwik, C. Ramesh, M. Shorty, R. Curpăn, C. Bologa, L.A. Sklar, T. Oprea, E.R. Prossnitz, J.B. Arterburn,
JOrg. Biomol. Chem., 2010, 8(9), 2252-2259.
ChemProt: a disease chemical biology database,
O. Taboureau, S.K. Nielsen, K. Audouze, N. Weinhold, D. Edsgard, F.S. Roque, I. Kouskoumvekaki, A. Bora, R. Curpăn, T.S, Jensen, S. Brunak, T.I. Oprea,
Nucleic Acids Res., 2010, 39
The selective estrogen receptor modulator bazedoxifene inhibits hormone-independent breast cancer cell growth and down-regulates estrogen receptor α and cyclin D1,
J.S. Lewis-Wambi, H. Kim, R. Curpăn, R. Grigg, M.A. Sarker, C.V. Jordan,
Mol. Pharmacol., 2011, 80(4), 610-620.
A QSAR study using MTD method and Dragon descriptors for a series of selective ligands of α2C adrenoceptor,
A. Borota, M. Mracec, A. Gruia, R. Rad-Curpăn, L. Ostopovici-Halip, M. Mracec,
Eur. J. Med. Chem, 2011, 46(3), 877-884.
Structural determinants of the alpha2 adrenoceptor subtype selectivity,
L. Ostopovici-Halip, R. Curpăn, M. Mracec, C.G. Bologa,
J. Mol. Graph. Model., 2011, 29(8), 1030-1038.
MTD-PLS and docking study for a series of substituted 2-phenylindole derivatives with estrogenic activity,
E. Seclaman, A. Bora, S. Avram, Z. Simon, L. Kurunczi,
Chem. Papers, 2011, 65(4), 566–576.
High-throughput screen for the chemical inhibitors of antiapoptotic bcl-2 family proteins by multiplex flow cytometry, Assay and Drug Development Technologies,
R.F. Curpăn, P.C. Simons, D.Zhai, S.M. Young, M.B. Carter, C.G. Bologa, T.I. Oprea, A.C. Satterthwait, J.C. Reed, B.S. Edwards, et al,
Assay and Drug Development Technologies, 2011, 9(5), 465-474.
PLS-DA - Docking Optimized Combined Energetic Terms (PLSDA-DOCET) Protocol: A Brief Evaluation,
Sorin Avram, Liliana M. Pacureanu, Edward Seclaman, Alina Bora, and Ludovic Kurunczi,
Journal of Chemical Information and Modeling 2011 51 (12), 3169-3179.
Modelling heterocyclic azo dye affinities for cellulose fibres by computational approaches,
S. Funar-Timofei, W.M.F. Fabian, L. Kurunczi, M. Goodarzi, S.T. Ali, Y Van Hayden,
Dyes and Pigments, 2012, 94, 278-289.
In silico classification and virtual screening of maleimide derivatives using projection to latent structures discriminant analysis (PLS-DA) and hybrid docking,
Liliana Pacureanu, Luminita Crisan*, Alina Bora, Sorin Avram & Ludovic Kurunczi,
Monatshefte für Chemie, 143, 1559–1573 (2012).
3D homology model of the α2C-adrenergic receptor subtype,
L. Halip, A.T. Gruia, A. Borota, M. Mracec, R.F. Curpăn, M. Mracec,
Rev.Roum.Chim., 2012, 57(7-8), 763-768.
QSAR study and molecular docking on indirubin inhibitors of Glycogen Synthase Kinase-3,
L. Crisan, L. Pacureanu, A. Bora, S. Avram, L. Kurunczi, Z. Simon,
Cent. Eur. J. Chem., 2013, 11, 63-77.
Challenges in docking 2’-hydroxy and 2’,4’-dihydroxychalcones into the binding site of ALR2,
Sorin Avram, Luminita Crisan, Liliana Pacureanu, Alina Bora, Eduard Seclaman, Monica Balint, Ludovic Kurunczi,
Med Chem. Res., 2013, 22, 3589–3605.
Implementation of PLS discriminant analysis to rank indirubin derivatives against decoys,
L. Crisan, L. Pacureanu, A. Bora, S. Avram, L., Kurunczi,
Cent. Eur. J. Chem., 2013, 11(10), 1644-1656.
Molecular mechanism of action of bisphenol and bisphenol a mediated by oestrogen receptor alpha in growth and apoptosis of breast cancer cells,
S. Sengupta, I. Obiorah, P.Y. Maximov, R. Curpăn, V.C. Jordan,
British Journal of Pharmacology, 2013, 169(1), 167-178.
Modeling Of 2-Pyridin-3-Yl-Benzo[D][1,3]Oxazin-4-One Derivatives By Several Conformational Searching Tools And Molecular Docking,
Goodarzi, M.; Bora, A.; Borota, A.; Funar-Timofei, S.; Avram, S.; Vander Heyden, Y.,
Current Pharmaceutical Design, 2013, 19, 2194-2203.
Retrospective group fusion similarity search based on eROCE evaluation metric,
Sorin I. Avram, Luminita Crisan, Alina Bora, Liliana M. Pacureanu, Stefana Avram, Ludovic Kurunczi*,
Bioorganic & Medicinal Chemistry 2013, 21, 5, 1268-78.
Modeling of 2-Pyridin-3-yl-Benzo[d][1,3]Oxazin-4-one Derivatives by Several Conformational Searching Tools and Molecular Docking,
Mohammad Goodarzi, Alina Bora, Ana Borota, Simona Funar-Timofei, Sorin Avram and Yvan Vander Heyden,
Current Pharmaceutical Design, 2013; 19(12), 2194-2203.
Pharmacological relevance of endoxifen in a laboratory simulation of breast cancer in postmenopausal patients,
P.Y. Maximov, R.E. McDaniel, D.J. Fernandes, P. Bhatta, V.R. Korostyshevskiy, R.F. Curpăn, V.C. Jordan,
J. Natl. Cancer Inst., 2014, 106(10).
Influence of the length and positioning of the antiestrogenic side chain of endoxifen and 4-hydroxytamoxifen on gene activation and growth of estrogen receptor positive cancer cells,
P.Y. Maximov, D.J. Fernandes, R.E. McDaniel, C.B. Myers, R.F. Curpăn, V.C. Jordan,
J. Med. Chem., 2014, 57(11), 4569–4583.
Defining the conformation of the estrogen receptor complex that controls estrogen-induced apoptosis in breast cancer,
I. Obiorah, S. Sengupta, R. Curpăn, V.C. Jordan,
Mol. Pharmacol., 2014, 85(5), 789-799.
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Pana A.M., Badea V., Banica R., Bora A., Dudas Z., Cseh L., Costisor O.,
J. Photochem. Photobiol. A, 2014, 283, 22-28.
Modeling of ligand binding to the dopamine D2 receptor,
L. Ostopovici-Halip, R. Rad-Curpăn,
J. Serbian Chem. Soc. 2014, 79(2), 175-183.
Quantitative estimation of pesticide-likeness for agrochemical discovery,
Avram, S.; Funar-Timofei, S.; Borota, A.; Chennamaneni, S. R.; Manchala, A. K.; Muresan, S.,
Journal Of Cheminformatics, 6, 42 (2014).
Exploring the biological promiscuity of high-throughput screening hits through DFT calculations,
Ramona Curpăn, Sorin Avram, Robert Vianello, Cristian Bologa,
Bioorganic & Medicinal Chemistry 2014, 22, 8, 2461-68.
ColBioS-FlavRC: A Collection Of Bioselective Flavonoids And Related Compounds Filtered From High-Throughput Screening Outcomes,
Sorin I. Avram, Liliana M. Pacureanu, Alina Bora, Luminita Crisan, Stefana Avram and Ludovic Kurunczi*,
Journal Of Chemical Information And Modeling 2014, 54, 8, 2360-70.
PLS and shape-based similarity analysis of maleimides – GSK-3 inhibitors,
Luminita Crisan, Liliana Pacureanu, Sorin Avram, Alina Bora, Speranta Avram & Ludovic Kurunczi,
JJournal of Enzyme Inhibition and Medicinal Chemistry, 29, issue 4, (2014), 599–610.
